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15 Night Panama Canal Eastward Cruise

From £1,483pp

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Panama City
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The Most Innovative & Unique Ships At Sea*

An incredible & diverse array of full-board dining options Included*

Award-winning Broadway style musicals, London stage-shows & more*

Sumptuous accommodation to suit any needs*

Cruise Overview

  • Duration 15 nights
  • Departs 07 Oct 2027
  • Sails from San Diego, California
  • Ship Serenade of the Seas
  • Flights and transfersNo
  • Cruise code ‍2312826
  • Voyage code ‍SR15T253
  • Countries visited USA, Mexico, Colombia, Cayman Islands

Your Itinerary

A panoramic view of downtown San Diego

San Diego, California Thu 07 Oct 2027

A panoramic view of downtown San Diego

Nestled along California's sun-kissed coastline, San Diego enchants visitors with its blend of laid-back beach vibes and vibrant urban culture.

Serenade of the Seas, Royal Caribbean

At Sea Fri 08 Oct 2027

Serenade of the Seas, Royal Caribbean
Puerto Vallarta, Mexico

Puerto Vallarta, Mexico Sun 10 Oct 2027

Puerto Vallarta, Mexico

Puerto Vallarta – or simply Vallarta, as the locals call it – is a romantic's dream, with its cobblestoned lanes, beachfront eateries and an old city centre filled to the brim with charming boutiques. Jump onboard a Puerto Vallarta cruise and head to the shimmering waters of Yelapa beach for a dream-like escapade, or pop into Cafe des Artistes for a romantic meal in a candlelit garden. Then check out the landmark Los Arcos, a set of Roman-style arches by the waterfront, for a perfect photo of Vallarta's official symbol. For a break from the city life, head to Jardin Botanico Vallarta and enjoy the delightful scents of orchids and bromeliads and the refreshing waters of a boulder-filled river.

Serenade of the Seas, Royal Caribbean

At Sea Mon 11 Oct 2027

Serenade of the Seas, Royal Caribbean
Puerto Quetzal

Puerto Quetzal,Guatemala Wed 13 Oct 2027

Puerto Quetzal

Drive into the mountains to beautiful old Antigua, once the country's colonial capital, and discover its lovely bougainvillea draped buildings and breathtaking views of emerald volcanoes.

Serenade of the Seas, Royal Caribbean

At Sea Thu 14 Oct 2027

Serenade of the Seas, Royal Caribbean
Puntarenas, Costa Rica

Puntarenas, Costa Rica Fri 15 Oct 2027

Puntarenas, Costa Rica

Situated on the long Nicoya Peninsula, Puntarenas is a great jumping-off point for the eco-adventures that have made Costa Rica famous. Trek lush rainforests in San Luis Park. Discover tropical flora and fauna in Pos Volcano National Park, and shower under Costa Rica's tallest waterfall at Pura Vida Gardens and Waterfalls. Looking for oceanside adventure? Take the short drive from Puntarenas to the Nicoya Peninsula, where there's a wide array of beaches – relax on family-friendly Playa Guiones, or check out dramatic Playa Ostional, with its volcanic black sands and vibrant sea turtle population. Puntarenas cruises give you access to Playa Tamarindo, where you can find some of the best surf and food in the country.

Serenade of the Seas, Royal Caribbean

At Sea Sat 16 Oct 2027

Serenade of the Seas, Royal Caribbean
Panama Canal

Panama Canal (Cruising) Sun 17 Oct 2027

Panama Canal

Undeniably, Panama’s biggest attraction is the Panama Canal, a modern day wonder of the world. Constructed between 1903 and 1914, the canal’s three locks allow 14,000 boats a year to cross a 48 mile body of water from the Pacific Ocean to the Atlantic.

Cartagena, Colombia

Cartagena, Colombia Mon 18 Oct 2027

Cartagena, Colombia

On Colombia’s Caribbean-facing coast, Cartagena is a handsome and historic city, with distinctive Colonial architecture dating back to the sixteenth century.

Serenade of the Seas, Royal Caribbean

At Sea Tue 19 Oct 2027

Serenade of the Seas, Royal Caribbean
A panoramic view of the Cayman Islands

George Town, Grand Cayman Wed 20 Oct 2027

A panoramic view of the Cayman Islands

The Cayman Islands, a Caribbean paradise, beckon with their blend of natural splendour and financial prosperity.

Serenade of the Seas, Royal Caribbean

At Sea Thu 21 Oct 2027

Serenade of the Seas, Royal Caribbean
A panoramic view of Tampa

Tampa, Florida Fri 22 Oct 2027

A panoramic view of Tampa

Tampa, a vibrant city on Florida's Gulf Coast, captivates visitors with its eclectic blend of culture, history and coastal charm.

What's included *

  • Full board cruising on board Royal Caribbean’s Serenade of the Seas
  • Captain’s Welcome reception and sail away parties
  • Variety of INCLUDED dining options – treat yourself to a range of cuisines throughout your cruise
  • A range of bars, lounges & entertainment venues on board
  • On board salon, as well as a range of shops
  • Full entertainment programme – plenty of choice for how to spend your day, including swimming pools, Rock-Climbing wall and Mini Golf
  • Onboard shows including award-winning Broadway style musicals, London stage-shows, original Las Vegas productions and more
  • Vitality Spa, fitness centre, sports court & running track
  • Relax and unwind in the adults only solarium
  • Outdoor film nights INCLUDED
  • Babies and Tots programmes and the Adventure Ocean Youth Programme for younger guests
  • Plus, book an Ocean View or above by 8pm 30th June 2026 and receive a FREE John Lewis gift card worth up to £75

Book today and earn up to £59.71 off your next ROL Cruise booking

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Cabins & Prices

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* Prices shown are per person, based on two adults sharing a twin cabin and include all cruise offer discounts and savings.

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Interior

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Enjoy your vacation in the perfect space. Beds Two twin beds that convert to a Royal King bed. One Pullman bed in staterooms. Two Pullman beds in staterooms. Size Stateroom: 160 sq. ft.

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4V Deck 03

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3V Deck 03

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Studio Interior

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Enjoy your vacation in the perfect space. Beds One full size bed. Size Stateroom: 108 sq. ft.

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2W Deck 04

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Interior

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Two twin beds that convert to Royal King and private bathroom. Stateroom: 165 sq. ft.

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6V

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Interior Quad Guaranteed

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Interior Quad Guaranteed

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ZQ

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Interior

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Our most budget-friendly option A cozy and comfortable retreat Perfect for long naps after an adventure-filled day ( Up to 4 guests ) Beds One Royal King bed (can convert into two twin-size beds) One single sofa bed or one pull-down sofa bed in staterooms with up to 3 guests One double sofa bed or two fold-down Pullman beds in staterooms with up to 4 guests Size Stateroom: 170 sq. ft.

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5V Deck 02

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Family Ocean View

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Two twin beds (can convert into queen-size), additional bunk beds in separate area, separate sitting area with sofa bed, and a private bathroom with shower.

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FO

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Ultra Spacious Ocean View

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Have a spectacular view in an immense space with family. Beds Two twin beds that convert to a Royal King bed. One double sofa bed. One Pullman bed and one twin bed or two Pullman beds. Size Stateroom: 265 sq. ft.

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1K Deck 07

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Ocean View

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Gaze into the beautiful views from your cozy room. Beds Two twin beds that convert to a Royal King bed. One Pullman bed in staterooms. One double sofa bed or two Pullman beds in staterooms. Size Stateroom: 169 sq. ft.

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2N Deck 02

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1N Deck 02

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Spacious Ocean View

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Have a spectacular view for a memorable vacation. Beds Two twin beds that convert to a Royal King bed. One Pullman bed in staterooms. One double sofa bed or two Pullman beds in staterooms. Size Stateroom: 169 sq. ft.

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2M Deck 07

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Ocean View

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Gaze into the beautiful views from your cozy room. Beds Two twin beds that convert to a Royal King bed. One Pullman bed in staterooms. One double sofa bed or two Pullman beds in staterooms. Size Stateroom: 169 sq. ft..

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3N Deck 03

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Ocean View

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Two twin beds that convert to Royal King and private bathroom. Stateroom: 154 sq. ft.

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8N

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Ocean View Quad Guaranteed

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Ocean View Quad Guaranteed

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YQ

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Ocean View

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Ocean View - Accessible Budget-friendly with a view of the ocean Your very own in-stateroom window Great for families with small children ( Up to 4 guests ) Beds One Royal King bed (can convert into two twin-size beds) One pull-down sofa bed in staterooms with up to 3 guests One double sofa bed or two fold-down Pullman beds in staterooms with up to 4 guests Size Stateroom: 276 sq. ft.

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5N Deck 02

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Spacious Ocean View Balcony

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Immerse yourself in a gorgeous view for a memorable vacation. Beds Two twin beds that convert to a Royal King bed. One Pullman bed in staterooms. One double sofa bed or one single sofa bed and one Pullman bed in staterooms. One double sofa bed and one Pullman bed in staterooms. Size Stateroom: 204 sq. ft. Balcony: 41 sq. ft.

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4B Deck 09

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3B Deck 09

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Ocean View Balcony

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Experience a spectacular view for a memorable vacation. Beds Two twin beds that convert to a Royal King. One signle sofa bed in staterooms. One Pullman bed in staterooms. Size Stateroom: 179 sq. ft. Balcony: 20 sq. ft.

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5D Deck 07

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2D Deck 07

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6D

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Ocean View Balcony

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Experience a spectacular view for a memorable vacation. Beds Two twin beds that convert to a Royal King One signle sofa bed in staterooms. One Pullman bed in staterooms. Size Stateroom: 179 sq. ft. Balcony: 20 sq. ft.

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3D Deck 07

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Ocean View Balcony Quad Guaranteed

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Ocean View Balcony Quad Guaranteed

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XQ

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Spacious Sunset Balcony

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Spacious Sunset Balcony

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SG Deck 07

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Grand Suite - 1 Bedroom

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Enjoy a comfortable suite and the extra perks. Beds Two twin beds that convert to a Royal King bed. One double sofa bed. Size Stateroom: 293 sq. ft. Balcony: 106 sq. ft.

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GS Deck 10

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GS

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Owner’s Suite - 1 Bedroom

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Enjoy the ultimate suite for a perfect vacation. Beds One queen size bed. One double sofa bed. Size Stateroom: 582 sq. ft. Balcony: 154 sq. ft.

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OS Deck 10

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OS

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Royal Suite - 1 Bedroom

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Relish an extraordinary vacation in this luxurious suite. Beds One King bed. One double sofa bed. Size Stateroom: 1,001 sq. ft. Balcony: 106 sq. ft.

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RS Deck 10

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RS

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Junior Suite

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An incredible intimate suite with a great view. Beds Two twin beds that convert to a Royal King bed. One double sofa bed. Size Stateroom: 293 sq. ft. Balcony: 41 sq. ft.

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J3 Deck 10

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Owner’s Suite - 2 Bedroom

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Enjoy the ultimate suite for a perfect vacation with family and friends. Beds Two sets of two twin beds that convert to a Royal King bed. One double sofa bed. Two Pullman beds. Size Stateroom: 584 sq. ft. Balcony: 151 sq. ft.

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OT Deck 07

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Ocean View Suite - 2 Bedroom (No Balcony)

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Enjoy this incrediblely spacious room with your family. Beds Two twin beds that convert to a Royal King bed. One double sofa bed. One Pullman bed and one twin bed or two Pullman beds. Size Stateroom: 584 sq. ft.

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VT Deck 10

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The Ship - Serenade of the Seas

  • Occupancy2,110
  • Tonnage90,090 tons
  • Length965 ft (294.14 m)
  • Star RatingCrown IconCrown IconCrown IconCrown Icon

You can make every sea day count on board Serenade of the Seas. Take in wild views from the top of the rock climbing wall or dig into delicious dishes from around the world and when the sun sets, discover electrifying nightlife to keep the thrills going all night long.

What’s on board: Adventure Beach, Adventure Ocean, Business Services, Cafe Latte-Tudes, Card Room, Casino Royale, Centrum, Chef’s Table, Chops Grille, Cinema, Concierge Club, Conference Center, Crown & Castle Pub, Diamond Club, Fairways of Serenade, Fuel Teen Disco, Giovanni’s Table, Guest Services, Izumi, Kids’ Pool, Loyalty Desk, Medical Facility, Movie Screen, Next Cruise, Nursery, Park Cafe, Photo & Art Gallery, Portrait Studio, R Bar, RC Online, Reflections Dining Room, Rock Climbing Wall, Running Track, Schooner Bar, Shops of Centrum, Shore Excursions, Sky Bar, Solarium, Sports Court, Sports Deck, Swimming Pool, The Congo Bar, The Safari Club, Tropical Theatre, Video Arcade, Viking Crown Lounge, Vintages, Vitality at Sea Fitness Center, Vitality at Sea Spa, Vortex Nightclub, Whirlpool, Windjammer Cafe, Zanzibar Lounge and much, much more.

Serenade of the Seas

Experience the Difference

  • Our ABTA membership & ATOL licence protects all our packages or tailor-made holidays booked through ROL Cruise, so you can book with confidence knowing you are fully protected
  • Award-winning Cruise Miles® loyalty programme; with over 400,000 UK members
  • Winners of more than 50 Cruise Awards over the last 5 years
  • The UK's No.1 Independent Cruise Specialist; delivering impartial advice
  • Customer satisfaction at 98% and a Feefo score of 4.9/5.
  • Expert staff with over 1,000 years of combined travel expertise offering 5★ service
  • Flexible Payment Options Available
  • Celebrating 30 years as a cruise-only specialist
  • Insurance Guidance - ROL Cruise will assist you with obtaining insurance cover, including Covid-cover.
  • Key strategic partner with the major cruise lines
  • Ambassadors representing us and guiding our customers onboard and at key locations on their holidays

* Terms & Conditions

View cruise line T&Cs

Pre-paid gratuities are compulsory when booking anytime dining on board the following ships - Sailing in 2022: Anthem, Allure, Brilliance, Jewel, Odyssey, Vision & Voyager.

Please Note: The fares showing with flights and transfers included take the fare from the cheapest departure airport available - pricing may differ depending on your airport preference.

John Lewis Gift Card is based on one per booking, for UK mainland addresses only when booking an Oceanview or above by 8pm 30th June 2026. The amount is tiered on cabin grade booked.

View cruise line T&Cs
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